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Gorelick FS
Weve already covered the major ways to reduce free testosterone (and thereby decrease DHT)
General skincare measures can help support skin barrier function and reduce sensitivity: Moisturise regularly using fragrance-free, hypoallergenic emollients to maintain skin hydration, particularly if dryness accompanies weight loss Avoid harsh skincare products containing alcohol, strong fragrances, or exfoliating acids, which may exacerbate sensitivity Use broad-spectrum SPF 30+ sunscreen daily as a general skin protection measure, and limit prolonged sun exposure Wear loose, breathable clothing to minimise friction against sensitive skin areas Apply a cool compress to injection site reactions to help reduce localised redness or discomfort Maintain a balanced diet in line with the NHS Eatwell Guide
For adults with obesity or weightrelated comorbidities, the pipeline is moving faster than the care models built to receive it
Pharmacogenomic modeling, transcriptome analysis, and systems biology approaches will be crucial in understanding which patients are most likely to benefit from this treatment
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